Volume II Special Issue III March 2022

Name of Author : S Abibindhu, Smitha Nair & C Kannan

Title of the paper : Synthesis and Antioxidant Activity of Novel Chalcones Based Oxazine and Thiazine Derivatives

Abstract: The ability to inhibit oxidative stress has been established as the prime mechanism in treatment of several disease conditions.Condensation of substituted acetophenones and Ferrocene aldehyde resulted in the formation of various Chalcones I-III. The resulting various Chalcones I-III react with urea and Thiourea to form various oxaizines Ia-IIIa and various Thiazines Ib-IIIb. The reaction was monitored by TLC and synthesized products were characterized by physical, Elemental analysis, Spectral studies UV, FT-IR, C13 and 1H-NMR Spectroscopy. When these compounds were screened for antimicrobial activity and antioxidant susceptibilities by FRAP Assay.

Keywords : Ferrocene aldehyde, substituted acetophenones, Chalcones, Oxazines, Thiazines.

DOI :

Page Number : 9-15